To improve the accuracy to detect adrenal adenomas or nodular hyperplasia, we developed a novel high-resolution magnetic resonance imaging (MRI) protocol that uses dynamic contrast enhancement and diffusion-weighted imaging (DWI). We hypothesized that the application of these techniques that enhance spatial and temporal resolution would enable detection of aldosterone-producing lesions not observed by conventional methods. We describe four individuals with primary aldosteronism with contemporaneous, negative CTs that were found to have adrenal lesions by MRI.
