A Novel High-Resolution Magnetic Resonance Imaging Protocol Detects Aldosterone-Producing Adenomas in Patients With Negative Computed Tomography


To improve the accuracy to detect adrenal adenomas or nodular hyperplasia, we developed a novel high-resolution magnetic resonance imaging (MRI) protocol that uses dynamic contrast enhancement and diffusion-weighted imaging (DWI). We hypothesized that the application of these techniques that enhance spatial and temporal resolution would enable detection of aldosterone-producing lesions not observed by conventional methods. We describe four individuals with primary aldosteronism with contemporaneous, negative CTs that were found to have adrenal lesions by MRI.

Authors: Inbar Raber, Robert Tristan Isom, John D Louie, Shreyas Vasanawala, Vivek Bhalla
Keywords: MRI, magnetic resonance imaging, CT, computed tomography, aldosterone producing adenomas
DOI Number: 10.1093/ajh/hpy054      Publication Year: 2018

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