In this study, the investigators will compare endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) treatment in patients with primary aldosteronism (PA) with lateralization of their aldosterone overproduction to their left adrenal and a left-sided tumour visible by EUS, with conventional unilateral adrenalectomy. The primary objective of the study is to evaluate biochemical and clinical outcome after EUS-RFA treatment compared with unilateral adrenalectomy. Secondary objectives are to compare safety/procedural complications of the two procedures, length of hospital stay, rate of postoperative hypoaldosteronism and hypocortisolism after treatment, and change health-related quality of life compared with pre-treatment.
Status: Not yet recruiting Trial Number: NCT05368090
Conditions: Primary aldosteronism, Aldosterone-Producing Adenoma
Interventions: Procedure: EUS-RFA of left adrenal gland, Procedure: adrenalectomy
Locations: Haukeland University Hospital, Norway