What are the side effects of Spironolactone?

Common side effects of Spironolactone include:

  • Vomiting, diarrhea, and stomach pain or cramps
  • Dry mouth and thirst
  • Dizziness, unsteadiness, and headache
  • Gynecomastia (enlarged breast tissue) in men, and breast pain in women
  • Irregular menstrual periods and post-menopausal vaginal bleeding
  • Erectile dysfunction
  • Deepening of the voice and increased hair growth
  • Drowsiness, tiredness, and restlessness

Severe side effects of Spironolactone include:

  • Muscle pain or weakness
  • Numbness or tingling
  • Paralysis in the arms or legs
  • Arrhythmia
  • Confusion, extreme tiredness, and fainting
  • Unusual bleeding or bruising
  • Life-threatening skin reactions
  • Flu-like symptoms, pain in the upper right abdomen, loss of appetite, vomiting blood, or bloody stools
  • Difficulty breathing or swallowing
  • Decreased urination

Spironolactone has been found to cause tumor development in rats. As a result, the drug carries a black-box warning for tumor risk. Consult your physician or pharmacist for more detailed information on this medication.

For other answers to frequently asked questions, please visit our FAQs page.

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©2021-22
Primary Aldosteronism Foundation

The Primary Aldosteronism Foundation is a registered 501(c)(3) public charity. Donations are tax deductible in the US.

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