Summary

This study evaluates if :1 ) the plasma aldosterone concentration and blood pressure change in response to roxithromycin could be useful for the screening of PA patients carrying a KCNJ5-mutated APA; 2) the change of PAC in response to mutated KCNJ5 channel is truly occurring in KCNJ5-mutation APA.

Study Name: Macrolides for KCNJ5 – Mutated Aldosterone-Producing Adenoma (MAPA)
Status: Unknown
Conditions: Primary aldosteronism
Interventions: Drug: Clarithromycin
Locations: Department of Medicine – DIMED, University of Padova, Italy, Padova, Italy
Study link: https://ClinicalTrials.gov/show/NCT03414918

To search for other studies by topic, location, or status, go to our Clinical Studies page.

©2021 Primary Aldosteronism Foundation — All Rights Reserved

The Primary Aldosteronism Foundation is a registered 501(c)(3) public charity. Donations are tax deductible in the US.

©2021 Primary Aldosteronism Foundation

The Primary Aldosteronism Foundation is a registered 501(c)(3) public charity. Donations are tax deductible in the US.