Abstract/Summary:

Studies find surgery superior to medications in treatment of primary aldosteronism (PA). It would be ideal to compare surgical and medical therapy in patients with unilateral PA only, who have the option between these treatment modalities. However, this is challenging as most patients with unilateral PA on adrenal vein sampling (AVS) undergo surgery. The objective of the study was to compare outcomes of surgery and medications in patients with confirmed or likely unilateral PA. In patients with unilateral PA who can tolerate medications, medical therapy improves clinical and biochemical control, and may offer similar cardiovascular protection. However, surgery reduces pill burden, may cure hypertension, and is recommended for unilateral PA.

Authors: Troy H. Puar, Lih M. Loh, Wann J. Loh, Dawn S. T. Lim, Meifen Zhang, Pei T. Tan, Lynette Lee, Du S. Swee, Joan Khoo, Donovan Tay, Sarah Y. Tan, Ling Zhu, Linsey Gani, Thomas F. King, Peng C. Kek, Roger S. Foo
Keywords: aldosteronism, surgical vs medical treatment outcomes
DOI Number: 10.1111/cen.14351      Publication Year: 2020

To search for other research papers by topic, keyword, author, or year, please go to our Publications page.

©2021 Primary Aldosteronism Foundation — All Rights Reserved

The Primary Aldosteronism Foundation is a registered 501(c)(3) public charity. Donations are tax deductible in the US.

©2021 Primary Aldosteronism Foundation

The Primary Aldosteronism Foundation is a registered 501(c)(3) public charity. Donations are tax deductible in the US.