Aldosterone-Potassium Ratio Predicts Primary Aldosteronism Subtype


Prediction models have been developed to predict either unilateral or bilateral primary aldosteronism, and these have not been validated externally. We aimed to develop a simplified score to predict both subtypes and validate this externally. The novel aldosterone-to-lowest-potassium ratio is a convenient score to guide clinicians and patients of various ethnicities on the probability of primary aldosteronism subtype. Using APR to identify patients more likely to benefit from AVS may be a cost-effective strategy to manage this common condition.

Authors: Puar Troy H., Loh Wann J., Lim Dawn, Loh Lih M., Zhang Meifen, Foo Roger S., Lee Lynette, Swee Du S., Khoo Joan, Tay Donovan, Kam Jia W., Dekkers Tanja, Velema Marieke, Deinum Jaap, Kek Peng C.
Keywords: adrenal venous sampling, adrenalectomy, clinical prediction score, endocrine hypertension, subtyping
DOI Number: 10.1097/HJH.0000000000002348      Publication Year: 2020

To search for other research papers by topic, keyword, author, or year, please go to our Publications page.