Is it possible to have both adrenal glands removed?

If you have a bilateral form of primary aldosteronism that affects both your adrenal glands, you will be treated with medication rather than surgery. In most cases, treatment with mineralocorticoid receptor antagonists (MRAs), such as Spironolactone, will be able to control your blood pressure, keep your electrolytes in balance, and prevent other organ damage. Physicians will avoid removing both adrenal glands except under very serious circumstances, such as the presence of malignant tumors. Patients who have both adrenal glands removed must take replacement hormones for life. Unfortunately, medications aren’t able to replicate the daily rhythm of hormone production made by healthy adrenal glands or respond quickly to changes in the body’s needs under stress. As a result, these patients may have poor quality of life.