Clinical Study


The prevalence of hypertension dramatically increased. Although most cases of hypertension are idiopathic, some cases have an identifiable cause. Primary Aldosteronism (PA) is the most common cause of secondary hypertension and can be cured by surgery if PA is due to unilateral unique adrenal adenoma. Then this cause is worth identifying it. The surgery despite its minimally invasive nature is limited by the need for general anesthesia, the risk of vascular or visceral injuries, hematomas and all the adrenal gland is mostly removed. Imaged-guided percutaneous adrenal radiofrequency ablation (ARF) offers a less invasive alternative therapeutic option. This local therapy is employed to treat solid neoplasms whereas its application on functional adrenal adenoma is less documented and only a few case series with limited sample size are published. The impact on blood pressure control is not clearly reported. ARF ablation works by delivering a high-frequency alternating current through a needle electrode. An ionic agitation occurs and generates frictional heat for cell destruction at a predictable temperature and volume. Patients with a conventional documented due to unilateral adrenal nod who consented to the study were hospitalized. Patients with PE due to an aldosterone-producing adenoma are included in the study.

Study Name: Radiofrequency Ablation for Aldosterone-Producing Adenoma in Patients with Primary Aldosteronism
Status: Completed
Conditions: Primary Aldosteronism, Adrenal Adenoma
Interventions: Device: Radiofrequency ablation
Locations: CHU Bordeaux, Bordeaux, France, CHU de Toulouse, Toulouse, France
Study link:

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