Clinical Study

Summary

This prospective cohort study will investigate the physiology and progression of autonomous aldosterone secretion. This protocol is designed to be a prospective longitudinal study that will carefully characterize the degree of autonomous aldosterone secretion among high-risk normotensive individuals and follow them longitudinally with repeated phenotyping study visits to assess the progression and severity of autonomous aldosterone secretion over time and its relevance to cardiovascular health.

Study Name: Prospective Phenotyping of Autonomous Aldosterone Secretion

Status: Active Not Recruiting

Conditions: Aldosterone Disorder, Adrenal Gland Disease, High Blood Pressure

Interventions: Dietary Supplement: Sodium loaded diet; Dietary Supplement: Restricted sodium diet; Drug: Angiotensin II; Drug: Para-Aminohippurate

Locations: Brigham and Women’s Hospital, Boston, Massachusetts, USA

Study link: https://ClinicalTrials.gov/show/NCT03484130

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