OBJECTIVES: I. Determine the prevalence of glucocorticoid-remediable aldosteronism (GRA) invarious hypertensive populations and screen at risk members of GRA pedigrees.II. Investigate other factors regulating blood pressure in GRA (environmental, geneticallydetermined factors).III. Investigate renal and hormonal mechanisms regulating potassium homeostasis in GRA.IV. Describe clinical phenotype of GRA patients. V. Prospectively screen GRA-affectedpatients with MRI angiography for intracranial aneurysm.
Study Name: Study of Prevalence and Clinical Phenotype in Patients With Glucocorticoid-Remediable Aldosteronism
Conditions: Primary aldosteronism
Interventions: Observational only
Locations: Brigham and Women’s Hospital, Boston, Massachusetts, United States
Study link: https://ClinicalTrials.gov/show/NCT00004354
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