Clinical Study

Summary

OBJECTIVES: I. Determine the prevalence of glucocorticoid-remediable aldosteronism (GRA) invarious hypertensive populations and screen at risk members of GRA pedigrees.II. Investigate other factors regulating blood pressure in GRA (environmental, geneticallydetermined factors).III. Investigate renal and hormonal mechanisms regulating potassium homeostasis in GRA.IV. Describe clinical phenotype of GRA patients. V. Prospectively screen GRA-affectedpatients with MRI angiography for intracranial aneurysm.

Study Name: Study of Prevalence and Clinical Phenotype in Patients With Glucocorticoid-Remediable Aldosteronism

Status: Completed

Conditions: Primary aldosteronism

Interventions: Observational only

Locations: Brigham and Women’s Hospital, Boston, Massachusetts, United States

Study link: https://ClinicalTrials.gov/show/NCT00004354

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